Fig. 9: Model of the binding mechanism of MraZ to the DNA promoter. | Nature Communications

Fig. 9: Model of the binding mechanism of MraZ to the DNA promoter.

From: Structural basis for transcriptional regulation by the cell division regulator MraZ in Mycoplasma genitalium

Fig. 9: Model of the binding mechanism of MraZ to the DNA promoter.

a Scheme of the oligomer transition between the unbound octamer to the DNA-bound MraZ structures through the open ring mechanism described in the text. PDB codes are shown below each structure. b Cartoon representation of two orthogonal views of Alphafold-2 models of MraZ from M. gallisepticum, E. coli, B. subtilis and N. gonorrhoeae. Conserved arginine residues of the “cradle-like” DNA binding motif are depicted in stick representation.

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