Fig. 6: Multicomponent synergistic anti-bacteria activity of biomacromolecule ⊂ZPF-2 with different distribution of biomacromolecules for wound healing. | Nature Communications

Fig. 6: Multicomponent synergistic anti-bacteria activity of biomacromolecule ⊂ZPF-2 with different distribution of biomacromolecules for wound healing.

From: Multicomponent synergistic immobilization via in-situ and dynamic exchange strategies for constructing hierarchical biopharmaceuticals

Fig. 6: Multicomponent synergistic anti-bacteria activity of biomacromolecule ⊂ZPF-2 with different distribution of biomacromolecules for wound healing.

a Illustration of the synthesis of Tps@Nisin⊂ZPF-2 (Tps = trypsin). b Schematic diagram of the infected wound model with treatment project. c Microphotographs of the infected wound on different days (0, 3, 7, 10, and 14). d Schematic diagram of the wound-healing process of I ~ V groups. e Wound healing rate compared to the initial wounds. I: control; II: Nisin; III: ZPF-2; IV: Nisin⊂ZPF-2; V: Tps@Nisin⊂ZPF-2. All error bars mean ± s.d. received from three independent experiments (n = 4 rats). The significance was calculated by one-way ANOVA using Tukey’s multiple comparisons test. **p  <  0.01. ***p  <  0.001.****p  <  0.0001. Schematic illustration figures were created in BioRender. Yi Tan, X. (2025) https://BioRender.com/ehu871i.

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