Fig. 1: Schematic illustration.

a Preparation of MOFS by cation replacement and absorption. b High resistance of MOFS and its long-lasting in situ synthesis of beneficial bioproducts in the gut. c MOFS-mediated protection of intestinal hemostasis by improving gut microbiota composition, suppressing intestinal inflammation, and increasing the integrity of the gut barrier. Created in BioRender. Liu, J. (2026) https://BioRender.com/dprgxuh.