Fig. 3: Investigation of mirror symmetry breaking induced by CDTA.
From: Crystallization-driven template autocatalysis induces mirror symmetry breaking and amplification
a Circular dichroism (CD) spectra of the suspensions in chloroform of the isolated [NCA]CF (green) and [NCrac]CF (purple) obtained by CDTA, together with NCA crystallites (orange) obtained by solution crystallization (SC). b False color SEM images of the washed [NCA]CF. P- and M-helical fibers are colored with red and blue, respectively. Scale bar, 5 μm. c Plots of CD intensity at 680 nm and nucleation time against the molar ratio of NNA to DCTH ([NNA]/[DCTH]). d CD spectra of the suspensions in chloroform of the isolated [NCA]CF obtained by CDTA with (R)-terpinen-4-ol (R-dopant, red) or (S)-terpinen-4-ol (S-dopant, blue). e False color SEM images of the washed [NCA]CF obtained by CDTA with R-dopant (left) or S-dopant (right). P- and M-helical fibers are colored with red and blue, respectively. Scale bars, 10 μm. f Percentages of P-(red) and M-(blue) helical fibers obtained by CDTA of NNA with R-dopant (left) or S-dopant (right). The error bars represent the mean ± s.d. of three replicates. p values were calculated by the two-tailed t-test.
