Fig. 7: In vivo PA and MR imaging in atherosclerotic mice. | Nature Communications

Fig. 7: In vivo PA and MR imaging in atherosclerotic mice.

From: A hierarchical theranostic nanoagent for multimodal imaging and targeted foam cell intervention in atherosclerosis

Fig. 7: In vivo PA and MR imaging in atherosclerotic mice.The alternative text for this image may have been generated using AI.

Representative PA/US images of the carotid arteries in atherosclerotic mice, shown in a transverse and b sagittal section views, 12 h post-treatment with different formulations. The regions of interest (ROIs, indicated by the white square) highlight the right carotid arteries. Scale bars: 3 mm. Quantitative analysis of PA signal intensity in carotid plaques following various treatments in c the transverse section and d sagittal section (n = 3 mice). e The corresponding SNR of PA signals quantified according to the images in a and b (n = 3 mice). f MR images of the carotid arteries in atherosclerotic mice acquired before and 12 h after injection of Gd-DOTA, FA-P@M or FA-P@MC. g Quantitative analysis of MR signal intensity in carotid plaques after different treatments (n = 3 mice). All data are expressed as mean ± SD. For c, d, g statistical significance was determined using one-way ANOVA for multiple comparisons. Source data are provided as a Source Data file.

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