Table 3 Inulin-induced changes in GPR41/GPR43 expression in germ-free and specific pathogen-free mice

From: Small intestinal microbial fiber metabolism dysfunction in celiac disease

 

Mean change in normalized

GPR41 expression (Inulin–NAF)

Mean change in normalized

GPR43 expression (Inulin–NAF)

Condition

Germ-free

SPF

Germ-free

SPF

Duodenum

−0.3200 ± 1.590

p = 0.85

4.100 ± 1.718

p = 0.04

−27.74 ± 24.59

p = 0.29

11.24 ± 7.898

p = 0.19

Jejunum

−8.080 ± 34.25

p = 0.82

9.660 ± 5.523

p = 0.12

−0.5400 ± 16.15

p = 0.97

12.70 ± 5.347

p = 0.04

Ileum

−0.3200 ± 3.834

p = 0.94

4.020 ± 2.361

p = 0.13

−12.06 ± 7.419

p = 0.14

8.140 ± 2.821

p = 0.02

Proximal

Colon

−4.160 ± 6.766

p = 0.56

4.760 ± 1.664

p = 0.02

−10.62 ± 6.828

p = 0.16

6.900 ± 3.897;

p = 0.11

  1. Data is shown as the mean difference in normalized gene expression between mice fed inulin and no added fiber, plus or minus the SEM. For each location, data were compared using a two-tailed Student’s t Test for comparison within germ-free or SPF mice, with significant differences indicated in bold text.
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