Table 2 Clinical outcomes in 101 patients hospitalized at Boston Medical Center with evidence of Mycobacterium tuberculosis DNA in discarded respiratory samples
Outcome | Overall | M. tuberculosis detected | M. tuberculosis not detected | OR or mean/median difference | Pa |
|---|---|---|---|---|---|
N = 101 | N = 16 | N = 85 | (95% CI) | ||
Died during the index admission | 10 (9.9) | 1 (6.3) | 9 (10.6) | 0.57 (0.01, 4.65) | 0.51 |
Age at death | |||||
Median (range) | 68 (53–88) | 62 (62) | 70 (53–88) | – | – |
Mean {SD} | 68 {10} | 62 {NA} | 69 {11} | – | – |
Died during the study (as of April 2019) | 27 (26.7) | 6 (37.5) | 21 (24.7) | 1.82 (0.48, 6.34) | 0.29 |
Age at death | |||||
Median (range) | 66 (48–89) | 66 (51–80) | 60 (48–89) | 6 (−13.33, 10.95) | 0.67 |
Mean {SD} | 66 {12} | 66 {10} | 66 {13} | – | – |
Time to death (days) | |||||
Median [IQR] | 36 [14,201] | 390 [5,694] | 26 [14,102] | – | 0.3 |
Mean {SD} | 266 {462} | 521 {584} | 190 {406} | – | |
Range | 0–1658 | 5–1546 | 0–1658 | ||
Principal diagnosis at the time of death | |||||
Sepsis/septicemia/MOF | 7 (25.9) | 4 (66.6) | 3 (14.3) | 8.79 (1.32, 67.48) | 0.02 |
Tumor registry/unknown | 6 (22.2) | 1 (16.6) | 5 (23.8) | 1.07 (0.02, 10.57) | 1 |
GI perforation/obstruction | 2 (7.4) | 1 (16.6) | 1 (4.8) | 5.45 (0.07, 442.87) | 0.4 |
Pneumonia | 6 (22.2) | 0 (0) | 6 (28.6) | NA | 0.28 |
Cardiovascular/stroke | 3 (11.1) | 0 (0) | 3 (14.3) | NA | − |
COPD exacerbation | 1 (3.7) | 0 (0) | 1 (4.8) | NA | − |
Anoxic brain injury | 1 (3.7) | 0 (0) | 1 (4.8) | NA | − |
Trauma | 1 (3.7) | 0 (0) | 1 (4.8) | NA | − |
Hospital readmissions | n = 64 (70.3) | n = 11 (73.3) | n = 53 (69.7) | 1.19 (0.31, 5.67) | 1·0 |
Median (range) | 2 (0–26) | 4 (0–15) | 2 (0–26) | − | − |
Mean {SD} | 4.8 {5·4} | 4.7 {4.8} | 4.8 {5.6} | − | − |
