Fig. 5: DEG enrichment in biological functions in the progenitor and natural strains, but not in the MA lines.

Heatmap illustrating GO categories enriched in DEGs up-regulated under clotrimazole stress. Each column represents a sample, and each row represents a GO category. Green, purple, and yellow represent the progenitor BY4741, MA lines, and natural strains, respectively. Red highlights GO categories related to the general stress response. Enrichment in progenitor but not in MA lines was assessed using two-sided Fisher’s exact tests, P values were adjusted for multiple comparisons using the Benjamini–Hochberg false discovery rate method.