Table 2 Absolute Increases in Risk of Primary and Secondary Cardiovascular Outcomes in Relation to Maternal Agea

From: Maternal age and pregnancy-related cardiovascular complications

 

Maternal Age

Outcome

Overall (N = 2,710,983)

12–25 yrs (N = 736,715)

26–30 yrs (N = 811,169)

31–35 yrs (N = 748,595)

36–40 yrs (N = 346,717)

41–45 yrs (N = 63,227)

46–55 yrs (N = 4560)

Primary (any MACE)

3.83 (3.77–3.89)

2.91 (2.81–3.02)

3.22 (3.12–3.32)

3.95 (3.83–4.07)

5.96 (5.76–6.17)

8.64 (8.06–9.21)

9.43 (7.20–1.17)

Secondary

 Arterial events

0.41 (0.38–0.43)

0.33 (0.29–0.37)

0.36 (0.32–0.40)

0.38 (0.34–0.43)

0.62 (0.54–0.70)

0.78 (0.53–1.02)

2.19 (0.95–3.44)

 Venous events

1.50 (1.47–1.54)

1.29 (1.22–1.36)

1.31 (1.24–1.38)

1.54 (1.47–1.61)

2.04 (1.92–2.16)

2.88 (2.55–3.20)

4.39 (2.92–5.85)

 Other events

2.02 (1.98–2.07)

1.34 (1.27–1.40)

1.66 (1.59–1.73)

2.15 (2.07–2.23)

3.46 (3.31–3.61)

5.25 (4.81–5.69)

3.29 (1.86–4.72)

  1. aData are reported as number of events per 1000 pregnancies (95% confidence interval). MACE denotes major adverse cardiovascular event.
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