Fig. 5: Number of episodes of asthma worsening by season in patients within the two PrimoTinA-asthma trials48.
From: Asthma exacerbations and worsenings in patients aged 1–75 years with add-on tiotropium treatment
Number of adult patients with symptomatic severe asthma reporting at least one episode of asthma worsening receiving either tiotropium 5 µg once daily or placebo plotted by month. Data from the Southern Hemisphere were shifted by 6 months (July = Month 1, January = Month 7) to align the seasonal time periods based on meteorological definitions. Patients were recruited and commenced the 48-week treatment period across all months of the year. From ref. 48. Copyright © 2020. Reprinted with permission.
