Extended Data Fig. 8: Spatial analysis of key signalling pathways in AVE.
From: Spatial transcriptomic characterization of a Carnegie stage 7 human embryo
a. Bar plots showing the communication counts of source cells (left) and target cells (right) by ligand–receptor analysis. b. Bubble plots showing the communications between anterior visceral endoderm (AVE) and other clusters in human CS7 embryo. Red indicates target/receptor; Blue indicates source/ligand. The p values obtained from the permutation test were adjusted for multiple testing using the Benjamini–Hochberg method. c. Bubble plots showing the communications between anterior visceral endoderm (AVE) or definitive endoderm (DE2) (left) and other clusters in human CS7 embryo. Red indicates target/receptor; Blue indicates source/ligand. The p values obtained from the permutation test were adjusted for multiple testing using the Benjamini–Hochberg method.
