Extended Data Fig. 10: Fold change of the metabolites involving in proline and urea cycle pathways according to metabolomic analysis. | Nature Cell Biology

Extended Data Fig. 10: Fold change of the metabolites involving in proline and urea cycle pathways according to metabolomic analysis.

From: ALDH4A1 functions as an active component of the MPC complex maintaining mitochondrial pyruvate import for TCA cycle entry and tumour suppression

Extended Data Fig. 10: Fold change of the metabolites involving in proline and urea cycle pathways according to metabolomic analysis.

The targeted LC/MS metabolic profiling of proline, pyruvate, glutamate, arginine, ornithine and histidine from control, ALDH4A1 knockdown, ALDH4A1 knockdown Hep3B cells with restoration of ALDH4A1WT or ALDH4A1S352L. P-values were calculated by two-tailed unpaired t-test from 3 biological replicates (n = 3).

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