Extended Data Fig. 5: RASH3D19 deletion in combination with KRAS mutant inhibition inhibits spheroid growth.
From: RASH3D19 mediates RAS activation through a positive feedback loop in KRAS-mutant cancer
a,b, Time-lapse spheroid morphology images of sgControl and sgRASH3D19 AsPC1 (a) and PANC1 (b) cells untreated or treated with 10 nM MRTX1133. Pictures in red frame (Day 0 and Day 7 of both cell lines) were also represented in Fig. 3d.
