Extended Data Fig. 2: CS-enriched glycocalyx defines the lipid-rich, stressed tumour niche in GBM and CNS metastases. | Nature Cell Biology

Extended Data Fig. 2: CS-enriched glycocalyx defines the lipid-rich, stressed tumour niche in GBM and CNS metastases.

From: Tumour acidosis remodels the glycocalyx to control lipid scavenging and ferroptosis

Extended Data Fig. 2

a–d, Fluorescence imaging of tumour sections highlighting perinecrotic region (upper row; CA9+/CD31−/LD+/CS+) and vascular region (lower row; CA9−/CD31+/LD−/CS+) from GBM (a) (representative of >5 patients), and CNS metastases originating from kidney cancer (b), malignant melanoma (c), and lung cancer (d) (representative of 1-2 patients/tumour entity). Scale bars: 500 and 100 μm (zoomed). CS was visualized via scFv clone GD3G7 (a-d).

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