Extended Data Fig. 6: Results from a SLiM simulation mimicking the asexual, diploid yeast experimental evolution.
From: Adaptive tracking with antagonistic pleiotropy results in seemingly neutral molecular evolution
Ne = 4×105, genome size = 1.6×105, mutation rate = 1×10−7 per site per generation, and other conditions followed the basal AdapTrack and Adaptive models. The simulation was run for 800 generations, and the environment changed every 80 generations under AdapTrack but remained constant under Adaptive. a, Fractions of “substitutions” belonging to various categories, where “substitutions” refer to mutational differences between the progenitor and a single sampled individual at the end of the simulation. b, Ω computed from the “substitutions” above defined. Shown are the results from 100 simulation replications. In (b), the lower and upper edges of a box represent the first (Q1) and third (Q3) quartiles, respectively, the horizontal line inside the box indicates the median, the whiskers extend to the most extreme values inside inner fences from Q1 – 1.5 × (Q3 – Q1) to Q3 + 1.5 × (Q3 – Q1), and the dots show outliers.
