Extended Data Fig. 2: Alignment of the two hydrogenase [NiFe]-center coordination motifs (N-ter RxCGxCxxxH and C-ter DPCxxCxxH/R) from the AD family.
From: Evolution and diversity of oxidoreductases involved in redox balance and energy conservation
The alignment is split in three groups of AD representatives: A) those missing most of the conserved residues of the motifs (in particular the cysteines), B) those of membrane-bound hydrogenase complexes and C) those of cytosolic hydrogenase complexes. Conserved cysteines are in red, other residues mostly conserved in both membrane and cytosolic hydrogenase complexes are in blue, those mostly conserved in membrane-bound hydrogenase complexes are in yellow and those from cytosolic hydrogenase complexes are in pink.
