Extended Data Fig. 9: Hit rate of experimentally tested compounds plotted against DOCK scores with different affinity cutoffs.
From: The impact of library size and scale of testing on virtual screening
a, Hit rates of all compounds tested (1,447 well-behaved molecules among 1,521 purchased) plotted against DOCK scores with four different affinity cutoffs: < 400, <137, <40 and <13 μM. b, Hit rates of manually picked compounds (687 compounds) plotted against DOCK scores with four different affinity cutoffs: <400, <137, <40 and <13 μM.
