Extended Data Fig. 4: Multiplexed YES-gated release of proteins from hydrogel biomaterials. | Nature Chemical Biology

Extended Data Fig. 4: Multiplexed YES-gated release of proteins from hydrogel biomaterials.

From: Boolean logic-gated protein presentation through autonomously compiled molecular topology

Extended Data Fig. 4

a, mGreenLantern-A, mCherry-S, and mCerulean-T are tethered homogenously into an underlying PEG-based hydrogel network via SpyLigation, each exhibiting a different YES-gated response. b, Appropriate proteins are individually released when their corresponding input is present. Fully colored bars (green for mGreenLantern, red for mCherry, blue for mCerulean) indicate conditions expected to yield protein release, whereas opaque colored bars denote conditions not expected to result in release. Error bars correspond to ±1 standard deviation about the mean with propagated uncertainties for n = 3 experimental replicates.

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