Extended Data Fig. 3: GPR56 promotes migrasomes and retractosomes formation in multiple cell lines.
From: Adhesion GPCR-induced ectocytosis mediates intercellular GPCR signal propagation
Left panels: Representative confocal images of HeLa, A875 and U87 cells expressing PH-GFP or GPR56-Venus. Insets show enlarged regions. Scale bars, 10 μm. The right side demonstrates the associated statistical results. Data are presented as mean ± SEM; n = 41 (Hela-PH), n = 50 (Hela-GPR56), n = 42 (CHO-K1-PH), n = 42 (CHO-K1-GPR56), n = 54 (A875-PH), n = 52 (A875-GPR56), n = 44 (U87-PH), n = 41 (U87-GPR56) cells from three independent experiments. Statistical significance was determined by unpaired t test (two-tailed). ****P < 0.0001.
