Extended Data Fig. 3: Transcriptionally (mRNA+) and transcriptionally + translationally (mRNA+p24+) active HIV-1-infected cells following ART initiation. | Nature Medicine

Extended Data Fig. 3: Transcriptionally (mRNA+) and transcriptionally + translationally (mRNA+p24+) active HIV-1-infected cells following ART initiation.

From: Early intervention with 3BNC117 and romidepsin at antiretroviral treatment initiation in people with HIV-1: a phase 1b/2a, randomized trial

Extended Data Fig. 3: Transcriptionally (mRNA+) and transcriptionally + translationally (mRNA+p24+) active HIV-1-infected cells following ART initiation.

Changes in HIV-1-infected cells during the first 30 days of ART among the four groups shown as median (error bars represents interquartile ranges) number of CD3+CD8- T cells expressing either HIV-1 mRNA (a) or HIV-1 mRNA and Gag p24 protein (b). ART-control n = 4, ART + 3BNC117 n = 5, ART + RMD n = 4, ART + 3BNC117 + RMD n = 5. ART, antiretroviral therapy; RMD, romidepsin.

Back to article page