Extended Data Fig. 5: Forest Plot of OS in Key Patient Subgroups. | Nature Medicine

Extended Data Fig. 5: Forest Plot of OS in Key Patient Subgroups.

From: Sacituzumab tirumotecan in previously treated metastatic triple-negative breast cancer: a randomized phase 3 trial

Extended Data Fig. 5: Forest Plot of OS in Key Patient Subgroups.

Data cutoff: November 30, 2023; the protocol-specified interim analysis of OS. Statistical analysis was not performed when the number of patients in the subgroup was less than 10% of the total patients. HRs along with 95% CIs were estimated using an unstratified Cox proportional hazards model in each subgroup. CI, confidence interval; ECOG, Eastern Cooperative Oncology Group; HER2, human epidermal growth factor receptor 2; HR, hazard ratio; NE, not estimable; NR, not reached; OS, overall survival; PD-1: programmed death-1; PD-L1: programmed death-ligand 1; sac-TMT, sacituzumab tirumotecan; TNBC, triple-negative breast cancer.

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