Extended Data Fig. 4: Effect sizes of age at treatment initiation on weight loss amongst GLP1-RA users across studies by ancestries.
From: Association between plausible genetic factors and weight loss from GLP1-RA and bariatric surgery
Points represent beta coefficients in Kg and error bars represent the 95% confidence intervals. Negative beta coefficients indicate that baseline age is associated with greater weight loss, while positive beta coefficients indicate the opposite. Total N = 6 750, sample size per each cohort/ancestry can be found in Table 1. AoU: All of Us, ATLAS: UCLA-Atlas Biobank, BioMe: BioMe Biobank, ESTBB: Estonian Biobank, HUS: Helsinki University Hospital, MGBB: Mass General Brigham Biobank, QBB: Qatar Biobank, UKBB: UK Biobank, AFR: African, AMR: admixed American, EAS: East Asian, EUR: European, MID: Middle Eastern, SAS: South Asian.
