Extended Data Fig. 6: Median change and percentage change from baseline over time in exploratory biomarkers in serum and nasal secretion.
From: Stapokibart for moderate-to-severe seasonal allergic rhinitis: a randomized phase 3 trial
Changes of four grass pollen-specific immunoglobulin E (sIgE) in serum (a, c) and nasal secretion (b, d) were analyzed in patients with positive baseline sIgE ( ≥ 0.1 kU [kUA] l−1). e, f, Charcot-Leyden Crystal Protein (CLC) in serum and nasal secretion; cystatin SN (CST-1) in nasal secretion. Comparisons between groups were analyzed using two-sided Wilcoxon rank-sum test, and P values were nominal without adjustments for multiple comparisons. Error bars denote interquartile ranges.
