Extended Data Fig. 10: Myeloid reprogramming in a resistant lesion.
From: A therapeutic peptide vaccine for fibrolamellar hepatocellular carcinoma: a phase 1 trial
a. Representative results from imaging mass cytometry for select markers that denote macrophage subtypes in primary, responding, or resistant lesions from one patient. Scale bar: 100 μm. b. Scaled expression profiles for myeloid subtypes sub-clustered. c. Composition of macrophage subtypes shown as stacked barplots (left) and individual barplots (right). d. Per-cell correlation of myeloid marker expression in all macrophages. e. Violin plots showing per-cell macrophage expression of functional markers (metal intensity).
