Extended Data Fig. 3: Proteins associated with circulating testosterone and estradiol concentration in participants receiving GAHT. | Nature Medicine

Extended Data Fig. 3: Proteins associated with circulating testosterone and estradiol concentration in participants receiving GAHT.

From: Plasma proteome adaptations during feminizing gender-affirming hormone therapy

Extended Data Fig. 3

Volcano plots of significant proteins associated with A. testosterone and B. estradiol. Y-axis: log10 Benjamini-Hochberg p-value. X-axis: effect size (estimate value) derived from the mixed linear model. The dashed y-intercepts indicate an adjusted p < 0.05. Scatter plots of C. LEP and D. INSL3 correlation with estradiol, testosterone and prolactin concentrations. In each scatter plot the grey shaded error band represents the 95% confidence interval of the fit.

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