Fig. 2: Integrated neuromodulation system. | Nature Medicine

Fig. 2: Integrated neuromodulation system.

From: Vagus nerve-mediated neuroimmune modulation for rheumatoid arthritis: a pivotal randomized controlled trial

Fig. 2: Integrated neuromodulation system.

The integrated neuromodulation system consists of an implant and pod. The implant is placed in the pod to position and hold it in place on the left cervical vagus nerve to ensure direct contact for precise stimulation. The implant is approximately 2.5 cm in length and weighs 2.6 g. To charge the implant, patients wear a wireless device (charger) around the neck for a few minutes, once a week. The implant is programmed by healthcare providers (HCPs) using a proprietary application (programmer). Adapted from ref. 16, by permission of Cold Spring Harbor Laboratory Press.

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