Extended Data Table 3 Exploratory post-hoc calculations of the win ratio at each level of the hierarchical primary outcome for subgroups defined by FFR

From: Fractional flow reserve-guided percutaneous coronary intervention versus medical therapy for stable coronary artery disease: long-term results of the FAME 2 trial

  1. For FFR < 0.65, there were 224 participants in the PCI group and 205 in the medical therapy group, resulting in a total of 45,920 pairs (224 ×205). For FFR ≥ 0.65, there were 223 in the PCI group and 236 in the medical therapy group, resulting in a total of 52,628 pairs (223 ×236).
  2. Win ratios are unconditional unless otherwise specified. *Conditional win ratio for time to myocardial infarction calculated in patient pairs with ties on time to death. **Conditional win ratio for time to revascularization calculated in patient pairs with ties on both time to death and time to myocardial infarction. 95% CI, 95% confidence interval. FFR, fractional flow reserve.