Extended Data Fig. 4: Forest Plots of Hazard Ratios for relapse free (a) and overall survival (b) by baseline variables. | Nature Medicine

Extended Data Fig. 4: Forest Plots of Hazard Ratios for relapse free (a) and overall survival (b) by baseline variables.

From: Neoadjuvant ipilimumab plus nivolumab in melanoma: 5-year survival and biomarker analysis from the phase 2 PRADO-trial

Extended Data Fig. 4

a, Forest plot of risk for recurrence, calculated from surgery (n = 92). b, Forest plot of risk for death, calculated from registration (n = 99); by using univariable Cox-regression analysis expressed in hazard-ratios per variable (square), with a 95% confidence interval (horizontal line) and P value compared to the reference variable. * Time-dependent variable. EU, Europe; AUS, Australia; LN, lymph node; MPR, major pathologic response; pPR, pathologic partial response; pNR, pathologic non-response; irAE, immune related adverse events; IFNγ, interferon gamma gene signature; TMB, tumor mutational burden; PD-L1, Programmed Cell Death Ligand 1.

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