Extended Data Fig. 2: Clinical outcomes 3 months after the third FMD cycle.

CDAI score assessment at the end of the study (week 24); for participants in the FMD group, this corresponded to approximately 3 months after completion of the third FMD cycle. a–d, No significant differences were observed in the percentages of participants achieving clinical response (a, 56.9% versus 53.1%, P = 0.83) or clinical remission (b, 55.4% versus 43.8%, P = 0.39) between FMD and control groups after 3-month washout, regardless of mild (c, 54.6% versus 60.9%, P = 0.79) or moderate (d, 71.4% versus 33.3%, P = 0.10) disease severity. Results are shown as percentages of participants meeting the criteria for response. P values were calculated by Fisher’s exact test or chi-square test; NS: P ≥ 0.05. FMD, fasting-mimicking diet.