Extended Data Fig. 6: 6. Post-relapse CD138 + MM whole-genome sequencing (WGS) data for case MM-62.
From: Multimodal antigenic escape to GPRC5D-targeted T cell engagers in multiple myeloma
A. IGV screenshot showing focal deletion (6 Kb) spanning chr12:12,948,661-12,954,728 (GRCh38), encompassing GPRC5D locus. B. CNVkit copy number plot of post-relapse WGS data, showing a broad monoallelic deletion on chr12p that includes GPRC5D (top panel), along with a focal biallelic deletion restricted to the GPRC5D locus (bottom panel).
