Table 2 irAEs for treatment type (FMT-related only and FMT in combination with ICI-based therapy)
Adverse events likely caused by FMT Number of events/number of patients with an adverse event | ||||
Overall | Grade 1 | Grade 2 | Grade 3 | Overall |
Diarrhea | 1/1 | 0/0 | 0/0 | 1/1 |
Adverse events likely caused by immunotherapy treatment Number of events/number of patients with an adverse event | ||||
Grade 1 | Grade 2 | Grade 3 | Overall | |
Overall | 32/12 | 29/12 | 18/10 | 79/17 |
Colitis | 0/0 | 3/2 | 7/6 | 10/6 |
Diarrhea | 4/4 | 3/2 | 4/3 | 11/7 |
Fatigue | 7/4 | 3/2 | 1/1 | 11/5 |
Immune-related pain | 2/2 | 4/3 | 1/1 | 7/4 |
Rash/pruritis/urticaria | 8/5 | 2/2 | 1/1 | 11/8 |
Anorexia | 3/3 | 2/2 | 1/1 | 6/5 |
Arthritis | 0/0 | 1/1 | 1/1 | 2/2 |
Transaminitis | 1/1 | 0/0 | 1/1 | 2/2 |
Hypothyroidism | 0/0 | 2/2 | 0/0 | 2/2 |
Hyponatremia | 1/1 | 0/0 | 0/0 | 1/1 |
Dry mouth/mucositis | 2/2 | 1/1 | 0/0 | 3/2 |
Hyperglycemia | 0/0 | 1/1 | 1/1 | 2/2 |
Hot flashes | 0/0 | 1/1 | 0/0 | 1/1 |
Nausea | 1/1 | 1/1 | 0/0 | 2/1 |
Pneumonitis | 1/1 | 1/1 | 0/0 | 2/1 |
Adrenal insufficiency | 0/0 | 1/1 | 0/0 | 1/1 |
Dyspnea | 2/2 | 1/1 | 0/0 | 3/2 |
Gastrointestinal disorders | 0/0 | 1/1 | 0/0 | 1/1 |
Infusion-related reaction | 0/0 | 1/1 | 0/0 | 1/1 |
