Fig. 4: Relationship between UCs with high PPARγ protein expression, other molecular features and radiographic response to FX-909 (N = 29). | Nature Medicine

Fig. 4: Relationship between UCs with high PPARγ protein expression, other molecular features and radiographic response to FX-909 (N = 29).

From: A small-molecule inverse agonist of PPARγ for advanced solid tumors: a phase 1 trial

Fig. 4: Relationship between UCs with high PPARγ protein expression, other molecular features and radiographic response to FX-909 (N = 29).

Heat map showing samples grouped by molecular subtype and ordered by decreasing PPARγ protein expression on the basis of TPS (left to right). Molecular features are grouped into lineage-related features and immune-related features ordered by prevalence (for further details, see Supplementary Fig. 11b and Supplementary Table 10). cCR, confirmed complete response; cPR, confirmed partial response; NE, nonevaluable; NM, nonmeasurable disease; SD, stable disease; uPR, unconfirmed partial response; TMB, tumor mutational burden.

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