Extended Data Table 5 Mean (CV%) summary of plasma pharmacokinetic parameters of FX-909 in patients with advanced solid malignancies; including advanced urothelial carcinoma

From: A small-molecule inverse agonist of PPARγ for advanced solid tumors: a phase 1 trial

  1. N = number of participants; AUClast= area under the plasma time-concentration curve from time zero to the last quantifiable concentration; Cmax = maximum plasma concentration; PK = pharmacokinetics; t1/2 = terminal elimination half-life; Tmax = time to maximum plasma concentration; a Interim Analysis: Arithmetic Mean (CV%); b Median (Min, Max); c n = 3; d n = 9; e n = 8; f n = 4; g n = 6; h n = 7.