Correction to: Scientific Reports https://doi.org/10.1038/s41598-017-15760-4, published online 15 November 2017
This Article contains errors in Figure 2, wherein multiple panels are wrongly described due to errors in figure assembly:
In panel 2A (TLR4):
-The image labelled as pair-fed condition, scrambled, should have been described as EtOH-fed, scrambled.
-EtOH-fed, scrambled, should have been described as pair-fed, scrambled.
-Pair-fed, siRNA was wrongly included.
-EtOH-fed, siRNA should have been described as pair-fed siRNA.
In panel 2B (TLR2):
-The image described as EtOH-fed, scrambled, was wrongly included.
-Pair-fed, siRNA should have been described as EtOH-fed, scrambled.
-EtOH-fed, siRNA was mistakenly duplicated from the representative image of the pair-fed, scrambled condition in the same panel.
In panel 2C (RHAMM):
-The image labelled as pair-fed condition, scrambled, should have been included as pair-fed, siRNA in panel 2B.
-EtOH-fed, scrambled, should have been described as pair-fed, scrambled.
-Pair-fed, siRNA was wrongly included.
In panel 2D (CD44):
-The image described as pair-fed, scrambled, should have been included as EtOH-fed, scrambled in panel 2C.
-Pair-fed, siRNA, should have been included as pair-fed, siRNA in panel 2C.
The correctly compiled Figure 2 appears below.
siRNA knockdown of HA receptors in Kupffer cells from pair- and ethanol-fed rats. Wistar rats were allowed free access to a Lieber-DeCarli ethanol diet or pair-fed control diet for 4 weeks. Kupffer cells were isolated and nucleofected with 25 nM of scrambled siRNA or siRNA targeted to (A) TLR4, (B) TLR2, (C) RHAMM and (D) CD44. 24 h post-nucleofection, expression of (A) TLR4 (green), (B) TLR2 (red), (C) RHAMM (red) and (D) CD44 (red) was visualized by immunostaining with specific antibodies. Nuclei were labelled with DAPI (blue). All images were acquired using 20x objectives and are representative of 3 independent experiments.
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Saikia, P., Roychowdhury, S., Bellos, D. et al. Author Correction: Hyaluronic acid 35 normalizes TLR4 signaling in Kupffer cells from ethanol-fed rats via regulation of microRNA291b and its target Tollip. Sci Rep 15, 9766 (2025). https://doi.org/10.1038/s41598-025-94493-1
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DOI: https://doi.org/10.1038/s41598-025-94493-1
