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Knowledge, attitude, and practice of osteoporosis and hip fracture in older Chinese adults
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  • Published: 08 January 2026

Knowledge, attitude, and practice of osteoporosis and hip fracture in older Chinese adults

  • Feng Ma1,
  • Zhaofu Wang2,
  • Xiaohai Luo3,
  • Ning Wu4,
  • Xiaolin Ma4,
  • Yanjun Hu5,6 &
  • …
  • Bin Yu5,6 

Scientific Reports , Article number:  (2026) Cite this article

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We are providing an unedited version of this manuscript to give early access to its findings. Before final publication, the manuscript will undergo further editing. Please note there may be errors present which affect the content, and all legal disclaimers apply.

Subjects

  • Diseases
  • Health care
  • Medical research
  • Risk factors

Abstract

This study assessed the knowledge, attitude, and practices (KAP) regarding osteoporosis and hip fracture among older adults in Ningxia, China, to inform better prevention and management strategies through patient education and lifestyle changes. This cross-sectional study surveyed older adults at Ningxia Hui Autonomous Region People’s Hospital (Sep 2022–Nov 2023) using a convenience sampling method, collecting demographic data and assessing KAP scores. Structural equation modeling (SEM) analyzed relationships between KAP and demographics. The analysis included 522 (99.4%) valid questionnaires. The mean knowledge, attitude, and practice scores were 22.66 ± 4.29 (/30, 75.53%), the mean attitude score was 43.13 ± 4.54 (/60, 71.88%), and the mean practice score was 57.15 ± 10.24 (/80, 71.44%), indicating sufficient knowledge, positive attitude, and proactive practice. In the SEM, knowledge was associated with income (β = 1.01, P < 0.001), frequency of fall prevention (β=-0.55, P < 0.001), residence (β = 0.97, P = 0.030), and falls in the past year (β = 0.76, P = 0.017). Attitude was associated with knowledge (β = 0.21, P < 0.001) and alcohol (β=-1.26, P < 0.001). Practice was associated with attitude (β = 1.09, P < 0.001), frequency of fall prevention (β=-1.86, P < 0.001), and use of anti-osteoporosis drugs (β = 2.63, P < 0.001). Older adults in Ningxia demonstrated generally good KAP toward osteoporosis and hip fracture; however, targeted educational interventions addressing specific knowledge gaps may help further improve preventive practices and support behavior change.

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Data availability

All data generated or analyzed during this study are included in this article and supplementary information files.

References

  1. Camacho, P. M. et al. American association of clinical Endocrinologists/American college of endocrinology clinical practice guidelines for the diagnosis and treatment of postmenopausal Osteoporosis-2020 update. Endocr. Pract. 26, 1–46 (2020).

    Google Scholar 

  2. Watts, N. B. et al. Osteoporosis in men: an endocrine society clinical practice guideline. J. Clin. Endocrinol. Metab. 97, 1802–1822 (2012).

    Google Scholar 

  3. LeBoff, M. S. et al. The clinician’s guide to prevention and treatment of osteoporosis. Osteoporos. Int. 33, 2049–2102 (2022).

    Google Scholar 

  4. Looker, A. C., Isfahani, S., Fan, N. & Shepherd, B. Trends in osteoporosis and low bone mass in older US adults, 2005–2006 through 2013–2014. Osteoporos. Int. 28, 1979–1988 (2017).

    Google Scholar 

  5. Wright, N. C., Saag, K. G., Dawson-Hughes, B., Khosla, S. & Siris, E. S. The impact of the new National bone health alliance (NBHA) diagnostic criteria on the prevalence of osteoporosis in the USA. Osteoporos. Int. 28, 1225–1232 (2017).

    Google Scholar 

  6. Ensrud, K. E. et al. Implications of expanding indications for drug treatment to prevent fracture in older men in united states: cross sectional and longitudinal analysis of prospective cohort study. BMJ 349, g4120 (2014).

    Google Scholar 

  7. Salari, N. et al. Global prevalence of osteoporosis among the world older adults: a comprehensive systematic review and meta-analysis. J. Orthop. Surg. Res. 16, 669 (2021).

    Google Scholar 

  8. Zheng, M. et al. Differences in the prevalence and risk factors of osteoporosis in Chinese urban and rural regions: a cross-sectional study. BMC Musculoskelet. Disord. 24, 46 (2023).

    Google Scholar 

  9. Eastell, R. et al. Pharmacological management of osteoporosis in postmenopausal women: an endocrine Society* clinical practice guideline. J. Clin. Endocrinol. Metab. 104, 1595–1622 (2019).

    Google Scholar 

  10. Adler, R. A. Osteoporosis in men: a review. Bone Res. 2, 14001 (2014).

    Google Scholar 

  11. Gennari, L. & Bilezikian, J. P. New and developing pharmacotherapy for osteoporosis in men. Expert Opin. Pharmacother. 19, 253–264 (2018).

    Google Scholar 

  12. Florschutz, A. V., Langford, J. R., Haidukewych, G. J. & Koval, K. J. Femoral neck fractures: current management. J. Orthop. Trauma. 29, 121–129 (2015).

    Google Scholar 

  13. Sheehan, S. E., Shyu, J. Y., Weaver, M. J., Sodickson, A. D. & Khurana, B. Proximal femoral fractures: what the orthopedic surgeon wants to know. Radiographics 35, 1563–1584 (2015).

    Google Scholar 

  14. Sheng, B., Li, X., Nussler, A. K. & Zhu, S. The relationship between healthy lifestyles and bone health: A narrative review. Med. (Baltim). 100, e24684 (2021).

    Google Scholar 

  15. Andrade, C., Menon, V., Ameen, S. & Kumar Praharaj, S. Designing and conducting Knowledge, Attitude, and practice surveys in psychiatry: practical guidance. Indian J. Psychol. Med. 42, 478–481 (2020).

    Google Scholar 

  16. World Health Organization. Advocacy, communication and social mobilization for TB control: a guide to developing knowledge, attitude and practice surveys. http://whqlibdoc.who.int/publications/2008/9789241596176_eng.pdf. Accessed November 22, 20222008.

  17. Nohra, J., Sacre, Y., Abdel-Nour, A. & Mannan, H. Evaluation of Knowledge, Attitudes, and Practices Related to Osteoporosis and Correlates of Perceived High Risk among People Living in Two Main Districts of Lebanon. J Osteoporos. 2022, 1188482. (2022).

  18. Khan, Y. H., Sharriff, A., Khan, A. H., Mallhi, T. H. & Knowledge Attitude and practice (KAP) survey of osteoporosis among students of a tertiary institution in Malaysia. Trop. J. Pharm. Res. 13, 155–162 (2014).

    Google Scholar 

  19. Tay, C. L., Ng, W. L., Beh, H. C., Lim, W. C. & Hussin, N. Screening and management of osteoporosis: a survey of knowledge, attitude and practice among primary care physicians in Malaysia. Arch. Osteoporos. 17, 72 (2022).

    Google Scholar 

  20. Chan, C. Y. et al. Knowledge, Beliefs, Dietary, and lifestyle practices related to bone health among Middle-Aged and elderly Chinese in Klang Valley, Malaysia. Int J. Environ. Res. Public. Health 16, (2019).

  21. Ahmed, S. et al. Assessing the knowledge, attitude and practice of osteoporosis among Pakistani women: A National social-media based survey. PLoS One. 18, e0288057 (2023).

    Google Scholar 

  22. Al-Hemyari, S. S., Jairoun, A. A., Jairoun, M. A., Metwali, Z. & Maumoun, N. Assessment of knowledge, attitude and practice (KAP) of osteoporosis and its predictors among university students: cross sectional study. UAE J Adv. Pharm. Educ. Res. 8, 43–48 (2018).

    Google Scholar 

  23. Alani, Q. et al. Knowledge, Attitude, and practices towards osteoporosis among adults in the united Arab Emirates (UAE) in 2023. Cureus 16, e56084 (2024).

    Google Scholar 

  24. Xu, P., Zhao, N. & Wang, J. Knowledge, attitude, and practice toward osteoporosis among patients with chronic kidney disease in Zhejiang. Med. (Baltim). 103, e38153 (2024).

    Google Scholar 

  25. Wu, Y. et al. Attitudes, and practices of patients with knee osteoarthritis regarding osteoporosis and its prevention: A Cross-Sectional study in China. Int. J. Gen. Med. 17, 3699–3709 (2024).

    Google Scholar 

  26. Ran, J., Yang, X., Li, S. & Peng, W. A. Systematic review of research Tools, research status and improvement measures for osteoporosis awareness in Chinese and international. Int. J. Gen. Med. 18, 801–813 (2025).

    Google Scholar 

  27. Chandran, M. et al. Development of the Asia Pacific consortium on osteoporosis (APCO) framework: clinical standards of care for the screening, diagnosis, and management of osteoporosis in the Asia-Pacific region. Osteoporos. Int. 32, 1249–1275 (2021).

    Google Scholar 

  28. Cheng, X. et al. Chinese expert consensus on the diagnosis of osteoporosis by imaging and bone mineral density. Quant. Imaging Med. Surg. 10, 2066–2077 (2020).

    Google Scholar 

  29. Xie, Y. M. et al. [Clinical practice guideline for postmenopausal osteoporosis with traditional Chinese medicine]. Zhongguo Zhong Yao Za Zhi. 46, 5992–5998 (2021).

    Google Scholar 

  30. Svendsen, M. T. et al. Associations of health literacy with socioeconomic position, health risk behavior, and health status: a large National population-based survey among Danish adults. BMC Public. Health. 20, 565 (2020).

    Google Scholar 

  31. Clemens, K. K. et al. Hip fractures in older adults in Ontario, Canada-Monthly Variation, Insights, and implications. Can. Geriatr. J. 22, 148–164 (2019).

    Google Scholar 

  32. Azevedo, D. C. et al. G. Risk factors for osteoporotic hip fracture among community-dwelling older adults: a real-world evidence study. Adv. Rheumatol. 64, 8 (2024).

    Google Scholar 

  33. Beran, T. N. & Violato, C. Structural equation modeling in medical research: a primer. BMC Res. Notes. 3, 267 (2010).

    Google Scholar 

  34. Fan, Y., Chen, J. & Shirkey, G. Applications of structural equation modeling (SEM) in ecological studies: an updated review. Ecol. Process. 5, 19 (2016).

    Google Scholar 

  35. Kline, R. B. Principles and Practice of Structural Equation Modeling (Fifth Edition) (The Guilford Press, 2023).

    Google Scholar 

  36. Bergen, N. & Labonte, R. Everything is Perfect, and we have no problems: detecting and limiting social desirability bias in qualitative research. Qual. Health Res. 30, 783–792 (2020).

    Google Scholar 

  37. Latkin, C. A., Edwards, C., Davey-Rothwell, M. A. & Tobin, K. E. The relationship between social desirability bias and self-reports of health, substance use, and social network factors among urban substance users in Baltimore, Maryland. Addict. Behav. 73, 133–136 (2017).

    Google Scholar 

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Funding

This study was supported by the Ningxia Hui Autonomous Region’s Key R&D Program for Foreign Scientific and Technological Cooperation Projects (2022BFH02010).

Author information

Authors and Affiliations

  1. The First School of Clinical Medicine, Southern Medical University, Guangzhou, 510000, Guangdong, China

    Feng Ma

  2. The First Clinical Medical College, Lanzhou University, Lanzhou, 730000, Gansu, China

    Zhaofu Wang

  3. Orthopedics Department, People’s Hospital of Ningxia Hui Autonomous Region, Yinchuan, 750000, Ningxia, China

    Xiaohai Luo

  4. School of Surgery, Ningxia Medical University, Yinchuan, 750000, Ningxia, China

    Ning Wu & Xiaolin Ma

  5. Guangdong Provincial Key Laboratory of Bone and Cartilage Regenerative Medicine, Nanfang Hospital, Southern Medical University, No. 1023–1063, Shatai South Road, Baiyun District, Guangzhou, 510000, Guangdong, China

    Yanjun Hu & Bin Yu

  6. Department of Orthopaedics, Nanfang Hospital, Southern Medical University, No. 1023–1063, Shatai South Road, Baiyun District, Guangzhou, 510000, Guangdong, China

    Yanjun Hu & Bin Yu

Authors
  1. Feng Ma
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Contributions

Feng Ma, Zhaofu Wang, Xiaohai Luo, Ning Wu, and Xiaolin Ma carried out the studies, participated in collecting data, and drafted the manuscript. Feng Ma, Yanjun Hu, and Bin Yu performed the statistical analysis and participated in its design. Feng Ma and Zhaofu Wang participated in the acquisition, analysis, or interpretation of data and drafted the manuscript. All authors read and approved the final manuscript.

Corresponding authors

Correspondence to Yanjun Hu or Bin Yu.

Ethics declarations

Competing interests

The authors declare no competing interests.

Ethics approval and consent to participate

This work has been carried out in accordance with the Declaration of Helsinki (2000) of the World Medical Association. This study was approved by the Medical Ethics Committee of Ningxia Hui Autonomous Region People’s Hospital ([2021]-ZDYF-020), and all participants provided written informed consent.

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Cite this article

Ma, F., Wang, Z., Luo, X. et al. Knowledge, attitude, and practice of osteoporosis and hip fracture in older Chinese adults. Sci Rep (2026). https://doi.org/10.1038/s41598-026-35046-y

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  • Received: 14 August 2025

  • Accepted: 01 January 2026

  • Published: 08 January 2026

  • DOI: https://doi.org/10.1038/s41598-026-35046-y

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Keywords

  • Knowledge, attitude, practice
  • Osteoporosis
  • Hip fracture
  • Older adults
  • Cross-sectional study
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