Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

Advertisement

Scientific Reports
  • View all journals
  • Search
  • My Account Login
  • Content Explore content
  • About the journal
  • Publish with us
  • Sign up for alerts
  • RSS feed
  1. nature
  2. scientific reports
  3. articles
  4. article
A hybrid blockchain migration framework for converting traditional databases into blockchain-based EMR systems
Download PDF
Download PDF
  • Article
  • Open access
  • Published: 05 February 2026

A hybrid blockchain migration framework for converting traditional databases into blockchain-based EMR systems

  • Ahmed Al-Busaidi1,
  • Joseph Mani1,
  • Mohamed Sirajudeen Yoosuf1 &
  • …
  • Vijaya P1 

Scientific Reports , Article number:  (2026) Cite this article

We are providing an unedited version of this manuscript to give early access to its findings. Before final publication, the manuscript will undergo further editing. Please note there may be errors present which affect the content, and all legal disclaimers apply.

Subjects

  • Computational biology and bioinformatics
  • Engineering
  • Health care
  • Mathematics and computing

Abstract

Electronic Medical Records (EMRs) are crucial to modern healthcare. However, traditional relational databases fail to fulfill increased expectations for integrity, auditability, and compliance in regulated environments. This paper proposes a Hybrid Blockchain Migration Framework that integrates a conventional MySQL-based EMR system (OpenMRS) with a permissioned blockchain network (Hyperledger Fabric). Sensitive data fields are selectively mirrored to the blockchain, ensuring tamper-evident logging while retaining the high performance of SQL for routine operations. A middleware layer, implemented using Java Spring Boot, monitors changes in the EMR and commits cryptographic hashes and metadata to the blockchain in near real-time. We evaluate the hybrid system against both standalone MySQL and full-blockchain implementations using controlled benchmarks, analyzing latency, throughput, resource utilization, and auditability. Results show that the hybrid architecture sustains near-native responsiveness (median 2.1 ms versus 1.6 ms for pure MySQL and 60.5 ms for Fabric) and delivers 480 Transaction Per Second (TPS), while incurring only modest overhead (47% of i7-9750H CPU, 1.15 GB RAM) and enhancing data integrity and compliance with regulations such as Oman’s Personal Data Protection Law (PDPL). The framework is extensible to multi-institutional deployments and supports regulatory alignment, making it a viable pathway for blockchain adoption in clinical settings.

Data availability

The datasets generated and analysed during the current study were produced using a synthetic data generation script that creates artificial patient records based on common Omani first and family names. No real patient information or personally identifiable data were used. The synthetic dataset used for system benchmarking and blockchain migration testing is therefore fully de-identified and does not contain any real Electronic Medical Record (EMR) data. The data generation code, along with the sample synthetic dataset, is available in the [GitHub repository — link to be added upon acceptance]. Researchers can reproduce or extend the dataset by running the provided script, which uses randomized values for demographic and physiological parameters (e.g., height, weight, blood pressure) generated within medically plausible ranges. All synthetic data used in this study are compliant with the Oman Personal Data Protection Law (PDPL) since no identifiable or sensitive personal data were processed. Additional files or further materials are available from the corresponding author upon reasonable request.

References

  1. Hölbl, M., Kompara, M., Kamišalić, A. & Zlatolas, L. N. A systematic review of the use of blockchain in healthcare. Symmetry 10(10), 470 (2018).

    Google Scholar 

  2. Agbo, C. C., Mahmoud, Q. H. & Eklund, J. M. Blockchain technology in healthcare: A systematic review. Healthcare 7(2), 56 (2019).

    Google Scholar 

  3. Vazirani, A. A., O’Donoghue, O., Brindley, D. & Meinert, E. Implementing blockchains for efficient health care: Systematic review. J. Med. Internet Res. 21(2), e13529 (2019).

    Google Scholar 

  4. Daraghmi, E.-Y., Daraghmi, Y.-A. & Yuan, S.-M. MedChain: A design of blockchain-based system for medical records access and permissions management. IEEE Access 7, 164595–164613 (2019).

    Google Scholar 

  5. Siyal, A. A. Applications of blockchain technology in medicine and healthcare: Challenges and future perspectives. Cryptography 3(1), 3 (2019).

    Google Scholar 

  6. Ichikawa, D., Kashiyama, M. & Ueno, T. Tamper-resistant mobile health using blockchain technology. JMIR Mhealth Uhealth 5(7), e111 (2017).

    Google Scholar 

  7. Rouhani, S. MediChain™: A secure decentralized medical data asset management system. In Proc. IEEE Cybermatics (Blockchain 2018 Workshop), pp. 1348–1355 (2018).

  8. Azaria, A., Ekblaw, A., Vieira, T. & Lippman, A. MedRec: Using blockchain for medical data access and permission management. In Proc. 2nd Int. Conf. Open Big Data (OBD), pp. 25–30 (2016).

  9. Hasnain, M., Albogamy, F. R., Alamri, A., Ghani, I. & Mehboob, B. The Hyperledger Fabric as a blockchain framework preserves the security of electronic health records. Front. Public Health 11, 1272787. https://doi.org/10.3389/fpubh.2023.1272787 (2023).

    Google Scholar 

  10. Guo, H., Shi, H. & Zhao, C. Access control for electronic health records with hybrid blockchain-edge architecture. In Proc. IEEE Int. Conf. Blockchain, pp. 44–51 (2019).

  11. Wang, Q. & Qin, S. A Hyperledger Fabric-based system framework for healthcare data management. Appl. Sci. 11(24), 11693 (2021).

    Google Scholar 

  12. Sultanate of Oman, Issuing the Personal Data Protection Law. Sultani Decree No. 6/2022, Oman Official Gazette, (2022).

  13. Stamatellis, C., Papadopoulos, P., Pitropakis, N., Katsikas, S. & Buchanan, W. J. PREHEALTH: A privacy-preserving healthcare framework using Hyperledger Fabric. Sensors 20(22), 6587 (2020).

    Google Scholar 

  14. Mettler, M. Blockchain technology in healthcare: The revolution starts here. In Proc. IEEE 18th Int. Conf. e-Health Netw., Appl. Serv. (Healthcom), pp. 1–3 (2016).

  15. Lee, S., Kim, J. H., Kwon, Y., Kim, T. & Cho, S. Privacy preservation in patient information exchange systems based on blockchain: System design study. J. Med. Internet Res. 24(3), e29108 (2022).

    Google Scholar 

  16. Lopez, L. J. R., Millan Mayorga, D., Martinez Poveda, L. H., Amaya, A. F. C. & Reales, W. R. Hybrid architectures used in the protection of large healthcare records based on cloud and blockchain integration: A review. Computers 13(6), 15. https://doi.org/10.3390/computers13060152 (2024).

  17. OpenMRS Community. Our Impact – OpenMRS by the Numbers. OpenMRS. Available online: https://openmrs.org/what-we-do/our-impact/ (accessed on 7 December 2025).

  18. e-Estonia. KSI Blockchain Stack – Zero Trust Applications. Available online: https://digiexpo.e-estonia.com/cyber-security/ksi-blockchain-stack-zero-trust-applications/ (accessed on 8 December 2025).

  19. Ghafur, S. et al. A retrospective impact analysis of the WannaCry cyberattack on the NHS. NPJ Digit. Med. 2, 98 (2019).

    Google Scholar 

  20. National Audit Office. Investigation: The 2017 WannaCry cyber attack and the NHS. UK Parliament / NAO (2017).

Download references

Acknowledgements

During the preparation of this work, the author(s) used ChatGPT by OpenAI to improve language clarity and readability. After using this tool, the author(s) reviewed and edited the content as needed and take(s) full responsibility for the content of the publication.

Funding

The authors declare that no funds, grants, or other support were received during the preparation of this manuscript.

Author information

Authors and Affiliations

  1. Department of Mathematics and Computer Science, Modern College of Business and Science, Muscat, Oman

    Ahmed Al-Busaidi, Joseph Mani, Mohamed Sirajudeen Yoosuf & Vijaya P

Authors
  1. Ahmed Al-Busaidi
    View author publications

    Search author on:PubMed Google Scholar

  2. Joseph Mani
    View author publications

    Search author on:PubMed Google Scholar

  3. Mohamed Sirajudeen Yoosuf
    View author publications

    Search author on:PubMed Google Scholar

  4. Vijaya P
    View author publications

    Search author on:PubMed Google Scholar

Contributions

Ahmed Al-Busaidi conducted the research, designed and implemented the hybrid blockchain framework, performed the experiments, analyzed the results, and prepared the manuscript. Mani Joseph, Mohamed Sirajudee, and P. Vijaya. supervised the research, provided technical guidance, contributed to the interpretation of results, and reviewed and refined the manuscript. All authors approved the final version of the manuscript.

Corresponding author

Correspondence to Ahmed Al-Busaidi.

Ethics declarations

Competing interests

The authors declare no competing interests.

Additional information

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Al-Busaidi, A., Mani, J., Yoosuf, M.S. et al. A hybrid blockchain migration framework for converting traditional databases into blockchain-based EMR systems. Sci Rep (2026). https://doi.org/10.1038/s41598-026-36787-6

Download citation

  • Received: 24 October 2025

  • Accepted: 16 January 2026

  • Published: 05 February 2026

  • DOI: https://doi.org/10.1038/s41598-026-36787-6

Share this article

Anyone you share the following link with will be able to read this content:

Sorry, a shareable link is not currently available for this article.

Provided by the Springer Nature SharedIt content-sharing initiative

Keywords

  • Electronic medical records
  • Blockchain
  • Hybrid database
  • Hyperledger fabric
  • OpenMRS
  • Data migration
  • Healthcare IT
  • Data integrity
  • Oman PDPL
  • Compliance
Download PDF

Advertisement

Explore content

  • Research articles
  • News & Comment
  • Collections
  • Subjects
  • Follow us on Facebook
  • Follow us on Twitter
  • Sign up for alerts
  • RSS feed

About the journal

  • About Scientific Reports
  • Contact
  • Journal policies
  • Guide to referees
  • Calls for Papers
  • Editor's Choice
  • Journal highlights
  • Open Access Fees and Funding

Publish with us

  • For authors
  • Language editing services
  • Open access funding
  • Submit manuscript

Search

Advanced search

Quick links

  • Explore articles by subject
  • Find a job
  • Guide to authors
  • Editorial policies

Scientific Reports (Sci Rep)

ISSN 2045-2322 (online)

nature.com sitemap

About Nature Portfolio

  • About us
  • Press releases
  • Press office
  • Contact us

Discover content

  • Journals A-Z
  • Articles by subject
  • protocols.io
  • Nature Index

Publishing policies

  • Nature portfolio policies
  • Open access

Author & Researcher services

  • Reprints & permissions
  • Research data
  • Language editing
  • Scientific editing
  • Nature Masterclasses
  • Research Solutions

Libraries & institutions

  • Librarian service & tools
  • Librarian portal
  • Open research
  • Recommend to library

Advertising & partnerships

  • Advertising
  • Partnerships & Services
  • Media kits
  • Branded content

Professional development

  • Nature Awards
  • Nature Careers
  • Nature Conferences

Regional websites

  • Nature Africa
  • Nature China
  • Nature India
  • Nature Japan
  • Nature Middle East
  • Privacy Policy
  • Use of cookies
  • Legal notice
  • Accessibility statement
  • Terms & Conditions
  • Your US state privacy rights
Springer Nature

© 2026 Springer Nature Limited

Nature Briefing AI and Robotics

Sign up for the Nature Briefing: AI and Robotics newsletter — what matters in AI and robotics research, free to your inbox weekly.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing: AI and Robotics