Fig. 8: Heparin inhibition of p63C droplets seeded by p53C. | Communications Chemistry

Fig. 8: Heparin inhibition of p63C droplets seeded by p53C.

From: Oncogenic p53 triggers amyloid aggregation of p63 and p73 liquid droplets

Fig. 8

Bar plots show heparin’s effect on p63C aggregation when mixing p63C with (a) p53C or (b) p53C M237I in the presence of PEG. The data are shown as the mean ± s.e.m. of n = 3 independent experiments using the same protein batch. Microscopy images showing the AF488-labeled (c) p53C or (d) M237I, the Rhodamine-labeled p63C, the bright-field, and merged channels in the absence (-) or presence (+) of heparin. Scale bar: 20 μm.

Back to article page