Table 12 Examples of cereblon-based PROTACs from non-classic synthetic approaches
From: Synthesis, biological evaluation and clinical trials of Cereblon-based PROTACs
- Note:
- BRD4 Bromodomain-containing protein 4, GSK-3 glycogen synthase kinase 3, PD-L1 programmed death-ligand 1, SIRT sirtuin, IC₅₀ half-maximal inhibitory concentration, DC₅₀ half-maximal degradation concentration, Dmax half-maximal achievable degradation.
