Fig. 2: Reactivity comparison between Ac-LYRAA-SVTT (2a) thioester and Ac-LYRAA-MPAA (2b) thioester. | Communications Chemistry

Fig. 2: Reactivity comparison between Ac-LYRAA-SVTT (2a) thioester and Ac-LYRAA-MPAA (2b) thioester.

From: Rapid vinyl thianthrenium tetrafluoroborate-promoted thioacid-based native chemical ligation and its applications in chemical protein synthesis

Fig. 2: Reactivity comparison between Ac-LYRAA-SVTT (2a) thioester and Ac-LYRAA-MPAA (2b) thioester.

a Reaction scheme of ligation. b Kinetic data for the ligation between 2a or 2b and 3a, with or without MPAA. The fraction ligated was determined by integrated areas of RP-HPLC peaks at λ = 214 nm, the average and standard deviation (bars) are indicated (n = 3 independent experiments).

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