Fig. 3: Some RNAs in combination with Fe2+ catalyze the oxidative decomposition of H2O2. | Communications Chemistry

Fig. 3: Some RNAs in combination with Fe2+ catalyze the oxidative decomposition of H2O2.

From: RNA−Iron complexes catalyse prebiotic oxygen generation

Fig. 3: Some RNAs in combination with Fe2+ catalyze the oxidative decomposition of H2O2.The alternative text for this image may have been generated using AI.

The 23S rRNA from T. thermophilus (purple), C-puromycin (CPmn; red), CCA trinucleotide (cyan), and puromycin (Pmn; green) catalyze the oxidative decomposition of H2O2 in the presence of Fe2+. The reaction was monitored using a modified “blue bottle” assay, which detects oxygen generation through the oxidation of methylene blue, measured by absorbance at 664 nm. The CA dinucleotide (pink) showed no catalytic activity. “Minus RNA” denotes the control reaction comprising Fe2+ and H2O2 in the complete assay mixture, but with no added RNA or RNA analog. Dashed lines represent raw experimental data; solid curves represent smoothed trends derived from the data.

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