Extended Data Fig. 3: Intestinal FPN deletion has no effects on chronic colitis. | Nature Metabolism

Extended Data Fig. 3: Intestinal FPN deletion has no effects on chronic colitis.

From: Fibroblast lipid metabolism through ACSL4 regulates epithelial sensitivity to ferroptosis in IBD

Extended Data Fig. 3: Intestinal FPN deletion has no effects on chronic colitis.

a, Relative gene expression and b, Protein expression of Ferroportin (Fpn) in colon tissue from Fpnf/f mice (n = 5) and VilERT2; Fpnf/f mice (n = 5). c, Representative H&E images, d, inflammatory histology scores, and e, colon lengths of VilERT2; Fpnf/f mice (n = 12) and Fpnf/f mice (n = 8) with chronic DSS-induced colitis. Data are shown as mean ± SEM, statistical analysis was performed using two-tailed unpaired T-test. All experiments were repeated at least twice independently, with similar results.

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