Extended Data Fig. 1: The identity of acyl-CoAs is confirmed by MS/MS.

a, Chemical structure of acyl-CoAs, in which “R” represents the acyl group. The adenine moiety is marked by dashed frame. The neutral loss of adenosine diphosphate (M = 507) is shown. b, MS/MS comparison of representative acyl-CoAs detected in samples (black) and commercial standards (red). The signature fragment peaks of adenine (M + H, M = 136) are highlighted in bold, and the neutral loss of adenosine diphosphate (M = 507) is highlighted in dashed arrow.