Extended Data Fig. 10: mRNA levels of genes in the Caco-2 cells treated with C. sphaerospermum culture supernatant, AMP, or PBS control.
a, Heatmap of the differentially expressed genes of Caco-2 cells treated with C. sphaerospermum culture supernatant, AMP, or PBS control (n = 3 biological replicates per group), as measured by bulk-RNA-seq. b, mRNA levels of barrier function-, and Wnt signaling pathway-related genes in Caco-2 cells treated with C. sphaerospermum culture supernatant, AMP, or PBS control (n = 3 biological replicates per group), as measured by qRT-PCR. Statistical significances were determined by two-tailed one-way ANOVA with Tukey’s multiple comparisons. For bar plots, data are presented as mean ± S.E.M.
