Extended Data Fig. 2: Related to HK2-mediated catalytic activity is necessary to support cell growth in HPLM. | Nature Metabolism

Extended Data Fig. 2: Related to HK2-mediated catalytic activity is necessary to support cell growth in HPLM.

From: Hexokinase detachment from mitochondria drives the Warburg effect to support compartmentalized ATP production

Extended Data Fig. 2: Related to HK2-mediated catalytic activity is necessary to support cell growth in HPLM.

(a) Pseudocolor Coomassie-stained gel imaged using a LI-COR Odyssey FC. 1: M.W. standards; 2: wild-type HK2-3xFLAG; 3: HK2 (D209A, D657A)-3xFLAG. (b) Schematic for a method to evaluate HK activity based on glucose 6-phosphate (G6P) production from reactions containing recombinant HK2.

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