Extended Data Fig. 6: Testosterone-associated gut microbial species identified using MaAsLin. | Nature Aging

Extended Data Fig. 6: Testosterone-associated gut microbial species identified using MaAsLin.

From: Sex- and age-related trajectories of the adult human gut microbiota shared across populations of different ethnicities

Extended Data Fig. 6

a-i, Scatterplot showing significant positive associations between testosterone level and nine bacterial species in the PG men after adjusting for 16 covariates (intake of alcohol, smoking, age, the first five principal components (PCs) of dietary habits, ‘daily sedentary time’, ‘hours of sleep per day’, BMI, TG, DBP, HOMA-IR, FT4 and hs-CRP) using MaAsLin (see details in Methods). BH adjusted P values from MaAsLin models (Pmaaslin) and Spearman’s correlation analysis (Pscc) are shown in each panel. BH adjusted P < 0.05 is considered as statistically significant. Blue dots, men. The detailed information of MaAsLin models including the BH adjusted P values, regression coefficient and the number of samples with measured taxon abundance greater than 0 is shown is shown in Supplementary Table 10.

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