Extended Data Fig. 9: Schematic diagram of the osteoclast-chondrocyte crosstalk mediated by osteoclast-derived exosomal miRNA in OA.

Left side of the dotted line: an illustration of the health articular joint. Right side of the dotted line: an illustration of the articular joint with OA. The box illustrates the postulated exosomal miRNA-mediated osteoclast-chondrocyte crosstalk in OA.