Extended Data Fig. 7: Drug-target gene interaction network for the drugs specifically targeting multicategory genes in age-dependent clusters.
From: Common genetic associations between age-related diseases
‘Drug-target gene’ interaction network for the drugs that specifically target multicategory cluster 1, cluster 2, or cluster ‘1 & 2’ genes as determined by Fisher’s exact test. Blue diamonds show the drugs with a significant association or targeting only one gene in these gene groups. Diamonds without written names are only represented with the ChEMBL IDs in the datasets and did not have names. Drug labels written in bold are drugs approved for different conditions. Circles represent the genes targeted by the significant hits, colored by their age-of-onset cluster. Gray circles show the genes targeted by these drugs but are not among the gene set of interest.
