Extended Data Fig. 1: Parity status does not impact loss of lineage fidelity in LEps. | Nature Aging

Extended Data Fig. 1: Parity status does not impact loss of lineage fidelity in LEps.

From: Evidence for accelerated aging in mammary epithelia of women carrying germline BRCA1 or BRCA2 mutations

Extended Data Fig. 1

(a-c) dot plots representing the distribution of (a) gravidity, (b) parity, and (c) time since last childbirth in years between average-risk (AR) and high-risk (HR) women included in this study. The lines on the plots represent the medians. (d-f) Correlation plots investigating the association of (d) gravidity, (e) parity, and (c) time since last childbirth in years and the percentage of luminal epithelial cells (LEps) expressing KRT14. The plots report Pearson correlation coefficient (r) and P values that were determined by a two tailed simple linear regression. The lines on the plots represent the best fit line computed via regression analysis.

Back to article page