Extended Data Fig. 1: Pathways predicted active in different age groups according to KEGG pathway analysis.

Red columns represented pathways more active in 20–40 yrs group, blue columns represented pathways more active in 40–60 yrs group, green columns represented pathways more active in 60+ yrs group. KEGG, Kyoto Encyclopedia of Genes and Genome. 20–40 yrs, n=46; 40–60 yrs, n=77; 60+ yrs, n=43.