Extended Data Fig. 1: K2 is highly expressed in mouse articular cartilage.
From: Kindlin-2 preserves integrity of the articular cartilage to protect against osteoarthritis
(a-b) Safranin O & Fast Green (SO&FG) and immunofluorescent (IF) staining of serial sections of mouse knee joint cartilage (a). Green double-headed arrow indicates hyaline cartilage; Red double-headed arrow indicates the calcified cartilage. White dashed lines indicate the cartilage surfaces. Red dashed line indicates the tide mark. Scale bar: 50 μm. Quantification of Kindlin-1-, 2- and -3-positive cells in articular cartilage (b). n = 4 biologically independent animals per group and results from one representative replicate are shown in a. Quantitative data are shown as mean ± standard deviation in b. The exact p values are shown. One-way ANOVA with Tukey’s multiple comparisons was used for statistical analysis.
